UCI researchers’ deep learning algorithm solves Rubik’s Cube faster than any human

Irvine, Calif., July 15, 2019 – Since its invention by a Hungarian architect in 1974, the Rubik’s Cube has furrowed the brows of many who have tried to solve it, but the 3D logic puzzle is no match for an artificial intelligence system created by researchers at the University of California, Irvine.

DeepCubeA, a deep reinforcement learning algorithm programmed by UCI computer scientists and mathematicians, can find the solution in a fraction of a second, without any specific domain knowledge or in-game coaching from humans. This is no simple task considering that the cube has completion paths numbering in the billions but only one goal state – each of six sides displaying a solid color – which apparently can’t be found through random moves.

For a study published today in Nature Machine Intelligence, the researchers demonstrated that DeepCubeA solved 100 percent of all test configurations, finding the shortest path to the goal state about 60 percent of the time. The algorithm also works on other combinatorial games such as the sliding tile puzzle, Lights Out and Sokoban.

“Artificial intelligence can defeat the world’s best human chess and Go players, but some of the more difficult puzzles, such as the Rubik’s Cube, had not been solved by computers, so we thought they were open for AI approaches,” said senior author Pierre Baldi, UCI Distinguished Professor of computer science. “The solution to the Rubik’s Cube involves more symbolic, mathematical and abstract thinking, so a deep learning machine that can crack such a puzzle is getting closer to becoming a system that can think, reason, plan and make decisions.”

The researchers were interested in understanding how and why the AI made its moves and how long it took to perfect its method. They started with a computer simulation of a completed puzzle and then scrambled the cube. Once the code was in place and running, DeepCubeA trained in isolation for two days, solving an increasingly difficult series of combinations.

“It learned on its own,” Baldi noted.

There are some people, particularly teenagers, who can solve the Rubik’s Cube in a hurry, but even they take about 50 moves.

“Our AI takes about 20 moves, most of the time solving it in the minimum number of steps,” Baldi said. “Right there, you can see the strategy is different, so my best guess is that the AI’s form of reasoning is completely different from a human’s.”

The veteran computer scientist said the ultimate goal of projects such as this one is to build the next generation of AI systems. Whether they know it or not, people are touched by artificial intelligence every day through apps such as Siri and Alexa and recommendation engines working behind the scenes of their favorite online services.

“But these systems are not really intelligent; they’re brittle, and you can easily break or fool them,” Baldi said. “How do we create advanced AI that is smarter, more robust and capable of reasoning, understanding and planning? This work is a step toward this hefty goal.”

Co-authors of the study were Forest Agostinelli, a UCI Ph.D. candidate in computer science; Stephen McAleer, a Ph.D. student in computer science; and Alexander Shmakov, a senior in mathematics.

About the University of California, Irvine: Founded in 1965, UCI is the youngest member of the prestigious Association of American Universities. The campus has produced three Nobel laureates and is known for its academic achievement, premier research, innovation and anteater mascot. Led by Chancellor Howard Gillman, UCI has more than 36,000 students and offers 222 degree programs. It’s located in one of the world’s safest and most economically vibrant communities and is Orange County’s second-largest employer, contributing $5 billion annually to the local economy. For more on UCI, visit www.uci.edu.

Media access: Radio programs/stations may, for a fee, use an on-campus ISDN line to interview UCI faculty and experts, subject to availability and university approval. For more UCI news, visit news.uci.edu. Additional resources for journalists may be found at communications.uci.edu/for-journalists.

Huntington Beach, Fountain Valley, Garden Grove, Westminster homebuying up 1% despite worst May for OC in 5 years

Homebuying in what we’ll call the “Coastline Blvd. Passage — “— in and around Huntington Coastline, Fountain Valley, Yard Grove and also — Westminster — climbed 1% as Orange Area sales stalled to the slowest pace given that 2014.

CoreLogic homebuying statistics show May was the 10th consecutive month Orange Region home sales stopped working to beat the rate of the year-ago duration. Plus, this was the slowest-selling Might countywide in five years as sales ran 13% below their historical month-to-month standard. Fewer buyers cut the countywide mean asking price by the biggest quantity in 7 years.

ICYMI: OC suffers nation’s 10th largest web population discharge

Just how do these homebuying patterns equate in your area? Well, CoreLogic discovered these 19 fads in 13 ZIP codes covered by the Orange Region Register’s The Wave weekly, for May …

… 1. Acquisitions: House sales for May amounted to 446 vs. 442 a year earlier, a gain of 1% in a year.

2. That’s up: Costs increased in 11 of the 13 ZIPs as sales climbed in seven ZIPs.

3. Countywide: $720,500 typical asking price, down 2.6% in a year. Orange Region saw 3,313 existing as well as new residences sell vs. 3,526 a year earlier, a decline of 6.0% in a year. Prices increased in 44 out of 83 Orange County ZIPs; sales were up in 40 out of 83 ZIPs.

Here is how rates as well as sales moved in the “Coastline Blvd. Passage” …

… 4. Fountain Valley 92708: $794,500 typical, up 7.7% in a year. Rate ranking? 31st of 83. Sales of 48 vs. 40 a year previously, a gain of 20.0% over 12 months.

5. Garden Grove 92840: $555,000 typical, up 1.8% in a year. Price rank? No. 68 of 83. Sales of 39 vs. 34 a year earlier, a gain of 14.7% over one year.

6. Yard Grove 92841: $641,000 average, up 3.4% in a year. Price rank? No. 58 of 83. Sales of 19 vs. 20 a year previously, a decline of 5% over twelve month.

7. Yard Grove 92843: $502,500 mean, down 8.6% in a year. Rate ranking? No. 78 of 83. Sales of 26 vs. 21 a year previously, a gain of 23.8% over twelve month.

8. Garden Grove 92844: $580,000 median, up 3.9% in a year. Price rank? No. 64 of 83. Sales of 15 vs. 20 a year earlier, a decrease of 25% over year.

9. Yard Grove 92845: $648,000 median, down 3.8% in a year. Price rank? No. 57 of 83. Sales of 17 vs. 14 a year earlier, a gain of 21.4% over 12 months.

10. Huntington Coastline 92646: $822,500 typical, up 7.9% in a year. Cost rank? No. 28 of 83. Sales of 73 vs. 91 a year previously, a decline of 19.8% over 12 months.

11. Huntington Coastline 92647: $760,000 mean, up 1.3% in a year. Rate ranking? No. 35 of 83. Sales of 43 vs. 26 a year previously, a gain of 65.4% over year.

12. Huntington Coastline 92648: $1,200,000 typical, up 20.6% in a year. Cost rank? No. 11 of 83. Sales of 50 vs. 59 a year earlier, a decrease of 15.3% over 12 months.

13. Huntington Coastline 92649: $817,500 typical, up 7.6% in a year. Rate rank? No. 30 of 83. Sales of 36 vs. 44 a year earlier, a decrease of 18.2% over one year.

14. Midway City 92655: $665,000 average, up 27.9% in a year. Cost rank? No. 55 of 83. Sales of 7 vs. 2 a year previously, a gain of 250.0% over year.

15. Stanton 90680: $442,000 mean, up 6.3% in a year. Cost ranking? No. 81 of 83. Sales of 16 vs. 19 a year earlier, a decrease of 15.8% over one year.

16. Westminster 92683: $670,000 mean, up 4.7% in a year. Cost ranking? No. 53 of 83. Sales of 57 vs. 52 a year previously, a gain of 9.6% over one year.
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Plus, 3 even more countywide patterns discovered in May vs. May 2018 …

… 17. Single-family-home resales: 2,107 Orange County sales vs. 2,135 a year earlier, a decline of 1.3% in the period. Average: $800,000 — — a rise of 0.6% in the duration.

18. Condo resales: 944 sales vs. 939 a year previously, a gain of 0.5% in a year. Average: $497,500 — — a dip of 1.5 %in 12 months.

19. New residences: Contractors sold 262 residences vs. 452 a year earlier, a decline of 42.0% in one year. Average: $944,000 — — a dip of 4.3% in 12 months.Related Articles Homebuying in Newport Beach, Laguna Beach, Costa Mesa up 1%despite countywide sales slump Homebuying in Lake Woodland, Objective Viejo, Rancho Santa Margarita, San Juan Capistrano drop 7% as countywide sales tumble to 5-year low Irvine, Tustin residence sales drop 11%; countywide pace slowest considering that 2014


  • Residences cost 9 times even more than 1 year’s pay in L.A.-Orange Region, Harvard study says< a course="article-title" href="https://www.ocregister.com/2019/06/19/o-c-housings-worst-slump-since-12-cut-sales-by-13-in-brea-buena-park-fullerton-la-habra-placentia-yorba-linda/" title="O.C. real estate's worst downturn given that '12 cut sales by 13% in Brea, Buena Park, Fullerton, La Habra, Placentia, Yorba Linda

  • ” > O.C. housing’s worst slump considering that ’12 cut sales by 13 % in Brea, Buena Park, Fullerton, La Habra, Placentia, Yorba Linda

    UCI team pioneers cancer treatment that targets bone metastases while sparing bone

    Irvine, Calif., July 8, 2019 — University of The golden state, Irvine scientists have actually developed and examined on computer mice a healing treatment that makes use of crafted stem cells to target as well as eliminate cancer bone metastases while maintaining the bone.This new approach

    , reported in the journal EBioMedicine, gears up crafted mesenchymal stem cells with targeting representatives that drive them to bone metastatic sites, where they unload rehabs. Link to research study: https://www.sciencedirect.com/science/article/pii/S2352396419304281?via%3Dihub”What’s powerful regarding this method is that we provide a mix

    of both anti-tumor and also anti-bone resorption representatives so we can efficiently obstruct the vicious cycle in between cancers as well as their bone niche,”said the research study’s lead author, Weian Zhao, associate teacher of pharmaceutical scientific researches and biomedical design.”This is a safe as well as virtually safe treatment contrasted to radiation treatment, which frequently leaves clients with long-lasting problems.”Sandra Spivey, an Orange Area person advocate that has actually been coping with metastatic bust cancer cells because 1997, has experienced firsthand the ravages of typical treatment.”Chemotherapy can eliminate both cancer cells and typical cells as well as produce radical adverse effects,”she claimed.”I have actually lost my hair; I have lost experience in my hands and feet. Many of all, radiation treatment actually robs you of your time. This new targeted approach might enhance lifestyle both during as well as after treatment.”The strategy might additionally be applied with other bone conditions that are generally tough to manage, such as numerous myeloma and weakening of bones.” This research study will certainly lead the way to a scientific test in the short term, as this sort of stem cell has already been checked as well as regarded safe in the facility,”Zhao stated.” UCI’s Division of Pharmaceutical Sciences, Sue & Bill

    Gross Stem Cell Proving Ground and also Chao Family Comprehensive Cancer Cells Facility are totally equipped to conduct this kind of medical trial. We will certainly want to target people with bone metastases.”Additionally contributing to the study were Aude Segaliny, Jason Cheng, Henry Farhoodi, Michael Toledano, Chih Chun Yu, Leanne Hildebrand, Linan Liu, Michael Liao, Jaedu Cho, Dongxu Liu, Lizhi Sunlight, Gultekin Gulsen and Min-Ying Su of UCI; as well as Beatrice Tierra and Dr. Robert Sah of UC San Diego. Assistance was supplied by the National Cancer Cells Institute(P30CA062203), the National Institutes of Health, the National Scientific Research Structure, the California Institute for Regenerative Medicine, Irvine-based Baylx Inc. as well as France’s ARC Structure for Cancer Research. About the University of The golden state

    , Irvine: Established in 1965, UCI is the youngest member of the prominent Organization of American Universities. The school has generated 3 Nobel laureates and also is known for its scholastic success, leading study, advancement and anteater mascot. Led by Chancellor Howard Gillman

    , UCI has even more than 36,000 pupils as well as uses 222 level programs. It lies in among the world’s most safe and most economically dynamic communities as well as is Orange Area’s second-largest employer, contributing$5 billion yearly to the regional economy. For much more on UCI, browse through www.uci.edu. Media accessibility: Radio programs/stations might, for a charge, utilize an on-campus ISDN line to interview UCI professors and experts, subject to accessibility and also university authorization. For even more UCI news, browse through news.uci.edu. Extra resources for reporters may be located at communications.uci.edu/for-journalists.

    We love Lucy…Jones: Doug McIntyre

    If Vin Scully is the most revered Southern Californian (and also he is) Dr. Lucy Jones is the most relied on. I want to buy your house alongside Lucy Jones. She’s got ta understand something, right?

    Lucy Jones has actually been calmly and calmingly discussing the mystical science of seismology to rattled Southern Californians on tv, radio as well as print given that 1983. Like Batman or Dr. Bombay from the old “Bewitched” series, Dr. Jones is always there when we require her, be it a vacation weekend break or 3 Get On a Tuesday. When the earth starts relocating Lucy Jones slides down the quake pole, completely dressed, large awake and quickly equipped with the that, what, when, where, why as well as just how of the most up to date shaker.

    After a 20 years respite, Southern The golden state was Rockin’ ‘n Rollin with a 6.4 Fourth of July foreshock complied with a couple of days later on by an attention-getting 7.1 main-quake. For the very first time since the Northridge temblor of 1994, “the Big One” was on everybody’s lips, even those people who have endured lots of P-waves and S-waves and are usually blasé concerning plate tectonics.

    We’re all poseurs obviously, because when the trembling starts, we instantly grab our reassurance, Dr. Lucy Jones of the U.S. Geological Survey and CalTech. We can only desire for having a Mayor, Governor or Head of state whose word is as relied on as Lucy Jones. A quote from Dr. Jones would certainly pass as collateral at any type of bank. In an age were no one trust funds anyone as well as hard-earned facts are coming to be a coin toss, a word or more from Lucy Jones works out nerves, reassures, notifies, and prods government and also specific citizens to take positive steps to conserve lives and fortunes. The amount of people can you name that are globally trusted?

    I’ll wait.

    “I assume my reputation is based in competence”, stated Dr. Jones in a phone interview last week. “There are several others with the very same proficiency, but I picked up from my papa, an engineer, to reject polysyllabic words and speak in ordinary English … It takes a great deal of effort to locate the fact.”

    And I believe her. Everybody does.

    The planet upon which we stand is just one of minority points we can rely on in a world for life in flux. Yet, as these latest quakes have as soon as again reminded us, also the strong earth is a deception. The ground under our feet can not be truly trusted. But rely on Dr. Jones has never ever been greater. In the age of “alternate facts”, “phony information” and also Web false information, Lucy Jones is as dependable as a metronome.

    “Scientific analysis is currently a need for everyone, not just researchers. In order to reduce with the quackery impersonating reality, we need to be able to vet resources,” stated Jones.

    There have actually been years when Dr. Jones was on TV greater than those Shen Yun commercials. Her capability to describe complex science in nonprofessional’s language– – without being supercilious even when oblivious reporters/radio hosts ask imbecilic concerns, guilty!– – Lucy Jones is the Julia Kid of seismology equalizing the strange forces at play miles under our feet, making plate tectonics not only understandable however survivable the same method Ms. Child introduced cuisine to America and also required Auntie Helen to up her game from tuna covered dish.

    Last year, the previous Los Angeles Quake Czar composed a book of her very own, “The Huge Ones: Exactly How Natural Disasters Have Shaped United States (And Also What We Can Do Regarding Them), an easy-to-read, must-have for all of us living inside the Ring of Fire. Dr. Jones is never alarmist yet neither is she a Pollyanna. Significant deadly quakes are uncommon yet they are a fact for this part of the world. (And numerous parts that remain blissfully however dangerously oblivious of the peril they encounter, like Memphis, Tennessee.)

    As great as Lucy Jones is on television as well as radio, she’s even better in the physics laboratory, having actually authored over one hundred documents on a selection of subjects, consisting of seismotectonics, which, honestly, I never ever heard of yet have actually included in this column to appear smarter than I am. Incidentally, Lucy also talks Chinese.

    Americans are a mobile people. Millions have been born here or moved here since the last huge quake in ’95. The rest of us give up to the peaceful passing years, numbed right into a false complacency. 20 years is a big piece of our lives but isn’t also a rounding mistake in geologic terms. The “Big One” will come, therefore will whole lots and also great deals of mid-sized quakes. In 2018, there were 16 quakes between 7.0 and 7.9 and 117 in between 6.0 and also 6.9.

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    The head of state and also the ambassador While we proceed to discover extra, develop brand-new modern technologies to caution us of an approaching quake as well as to make our structures and infrastructure more secure, the initial line of defense falls upon each of us. We are our very own first responders. Have you inspected your quake set? Do you have an earthquake set?

    Are you guaranteed for a great quake? Yes, it’s pricey however not as expensive as your residence being red-tagged. If Mayor Garcetti and Gov. Newsom think we have a housing situation now, wait until a major quake makes 100,000 or more existing devices unliveable.

    “Earthquakes are frightening due to the fact that they come on quickly with no warning”, stated Dr. Jones. “Truthfully, climate adjustment ought to scare us more, yet it’s beginning slowly with lots of warning so we appear not to care. If we don’t address climate adjustment there’s truly no point in fretting about quakes,” stated Jones with common bluntness. For those of you on the fence concerning international warming, consider the source.

    In a dissentious age, at the very least someone stays to unify us all. Left, Right, or Facility, Dodgers or Angels, Lakers or Clippers, USC or UCLA, all of us love Lucy.

    Doug McIntyre’s column shows up Sundays. He can be gotten to at: Doug@DougMcIntyre.com.

    UCI’s first Ono Pharma Breakthrough Science Initiative Award is won by associate professor

    Robert Spitale, associate teacher of pharmaceutical sciences, is among 5 victors of 2019 Ono Pharma Innovation Scientific Research Initiative Awards, intended to increase risky as well as high-reward science study tasks that could lead to explorations, remedies and prospective advancement therapies for clients. This is the very first time a UCI scientist has actually won the honor, which is for 3 years and also gives $900,000 in direct funds for picked projects. Spitale’s is labelled “Imaging and Genetically Characterizing Tumors With PET-Seq.” He will certainly work to better comprehend the technicians of positron emission tomography imaging. “ANIMAL imaging is regularly utilized by radiologists, oncologists and also specialists to overview treatment programs or medical resection,” Spitale claimed. “Regardless of the widespread use of PET DOG imaging, it deals with a number of drawbacks that, if boosted, would certainly have a significant result on execution, interpretation as well as use of these signals and guide individual therapy. About 2,500 PET scanners carry out regarding 2 million scans each year; thus, the effect of our suggested researches can be really significant.”